Study New Topic 14 Flash Cards

 
Pile Management Card
New Topic 14

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PCT, for every Na+ reabsorbed,
H+ secreted
HCO3- reabsorbed
Renal buffering system
-slow
-actively Secretes H+ against Na+
-reabsorbs HCO3
Respiratory System
-fast
-Central Receptor (Medulla oblongota) senes rise in [H+]
-peripheral chemoreceptors sense lower pH, pO2, higher pCO2
-buffering power 2x greater than all other buffering systems
Phospahte
-more important in kidneys
-kidney tubules has low pH--> closer to pH of buffer
HCO3 most important b/c...
...CO2, HCO3- regulated by lungs, kidneys
-Cl- shift favors HCO3- out of cell, into plasma
-HCO3 to CO2 is 20:1
Interstitial Fluid Buffers
1. HCO3-
2. HPO4-2 (kidneys)
3. NH3 (kidneys)
Blood Buffers
1. HCO3-
2. Hemoglobin
3. Protein (albumin)

(2 and 3 1st line of defense, but become easily saturated; hence, HCO3 becomes most important)
Intracellular Buffers
1. Proteins (75% of buffering power, but confined to cells; minor role in ECF buffering)
2. HPO4-2
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