Study BMB 402H Chapter 18 Flash Cards

 
Pile Management Card
BMB 402H Chapter 18

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physiological importance of branching in starch and glycogen
-the branches in glycogen and starch increase the rates of synthesis and degradation
-branches increase solubility
-increase number of non-reducing ends from which G1P can be derived during breakdown
dual role of glycogenin
1. primer for 1st glucose residue
2. catalyst to add up to 7 glucose residues
enzymes of glycogen synthesis
1. UDP-glucose pyrophosphorylase (vertebrates) or ADP-glucose pyrophosphorylase (microorganisms)

2. glycogenin

3. glycogen synthetase

4. branching enzyme
enzymes involved in glycogen degradation
1. glycogen phosphorylase
-catalyzes bond cleavage by phosphoryl group
-makes glucose-1-phosphate

2. phosphoglucomutatse
-makes glucose-6-phosphate

3. glycogen debranching enzyme
-phosphorylase stops cleaving (1-4) linkages four away from a branch point
glycogen structure
branches every 8-12 residues
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