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PCT, for every Na+ reabsorbed,
H+ secreted
HCO3- reabsorbed
0
mcs5109
Sun, 16 Nov 2008 08:02:39 GMT
Renal buffering system
-slow
-actively Secretes H+ against Na+
-reabsorbs HCO3
0
mcs5109
Sun, 16 Nov 2008 07:57:23 GMT
Respiratory System
-fast
-Central Receptor (Medulla oblongota) senes rise in [H+]
-peripheral chemoreceptors sense lower pH, pO2, higher pCO2
-buffering power 2x greater than all other buffering systems
0
mcs5109
Sun, 16 Nov 2008 07:57:23 GMT
Phospahte
-more important in kidneys
-kidney tubules has low pH--> closer to pH of buffer
0
mcs5109
Sun, 16 Nov 2008 07:57:23 GMT
HCO3 most important b/c...
...CO2, HCO3- regulated by lungs, kidneys
-Cl- shift favors HCO3- out of cell, into plasma
-HCO3 to CO2 is 20:1
0
mcs5109
Sun, 16 Nov 2008 07:57:23 GMT
Interstitial Fluid Buffers
1. HCO3-
2. HPO4-2 (kidneys)
3. NH3 (kidneys)
0
mcs5109
Sun, 16 Nov 2008 07:57:23 GMT
Blood Buffers
1. HCO3-
2. Hemoglobin
3. Protein (albumin)
(2 and 3 1st line of defense, but become easily saturated; hence, HCO3 becomes most important)
0
mcs5109
Sun, 16 Nov 2008 07:57:23 GMT
Intracellular Buffers
1. Proteins (75% of buffering power, but confined to cells; minor role in ECF buffering)
2. HPO4-2
0
mcs5109
Sun, 16 Nov 2008 07:57:22 GMT
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name: New Topic 14
num users: 2
num cards: 8
created on: November 15, 2008
last updated: November 16, 2008
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