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history |
| difference between parallel and antiparallel beta pleated sheet |
-antiparallel has straight hydrogen bonds -parallel has skewed hydrogen bonds |
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aschefkind Wed, 01 Feb 2012 02:50:19 GMT |
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| how many amino acids per turn in an alpha helix? |
3.6 |
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aschefkind Wed, 01 Feb 2012 02:40:12 GMT |
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| quaternary structure |
spatial arrangement of multiple polypeptide chains |
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aschefkind Wed, 01 Feb 2012 02:33:37 GMT |
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| tertiary structure |
bending path of the polypeptide chain in 3-D space |
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aschefkind Wed, 01 Feb 2012 02:33:37 GMT |
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| secondary structure |
regular, repeated local spatial patterns |
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aschefkind Wed, 01 Feb 2012 02:33:37 GMT |
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| primary structure |
linear sequence of amino acids |
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aschefkind Wed, 01 Feb 2012 02:33:37 GMT |
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| 2 cysteine amino acids bonded together make... |
a disulfide bridge |
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aschefkind Wed, 01 Feb 2012 02:26:41 GMT |
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| glucose+fructose |
sucrose |
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aschefkind Tue, 31 Jan 2012 05:19:37 GMT |
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| glucose+galactose |
lactose |
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aschefkind Tue, 31 Jan 2012 05:19:37 GMT |
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| inside of ER is called? |
lumen |
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aschefkind Tue, 31 Jan 2012 05:14:05 GMT |
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| Zwitterion |
a dipole with both a positive and a negative charge |
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aschefkind Tue, 31 Jan 2012 03:52:29 GMT |
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| basically all sugars are _____ isomers |
D |
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aschefkind Tue, 31 Jan 2012 03:51:59 GMT |
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| basically all amino acids are _____ isomers |
L |
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aschefkind Tue, 31 Jan 2012 03:51:59 GMT |
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| differences between archaea's phospholipids vs. bacteria? |
they have alcohols with branches instead of fatty acids (makes membranes fatter) these alcohols are linked to glyceride with ETHER BONDS rather than ester bonds. this makes them more resistant to oxidative damage |
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aschefkind Tue, 31 Jan 2012 03:51:16 GMT |
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| what happens if a protein's 3D structure is disrupted? |
if amino acid sequence remains, the protein will slowly regain its form because the sequence contains the information which specifies conformation |
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aschefkind Tue, 31 Jan 2012 03:51:16 GMT |
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| how does a protein know how to fold? |
it behaves with a tendency to retain partly correct intermediates |
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aschefkind Tue, 31 Jan 2012 03:51:16 GMT |
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| globular proteins |
compact, water soluble, perform most of cell's chemical transactions |
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aschefkind Tue, 31 Jan 2012 03:51:16 GMT |
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| lack of vitamin C causes.... |
scurvy b/c vitamin C acts as an antioxidant to create hydroxyproline in the formation of collagen fibers |
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aschefkind Tue, 31 Jan 2012 03:45:42 GMT |
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| superhelical coil |
3 helices wrapped around each other with glycine to fill up spaces
e.g. collagen |
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aschefkind Tue, 31 Jan 2012 03:45:42 GMT |
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| coiled coil |
2 alpha helices wrapped around each other
e.g. alpha keratin |
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aschefkind Tue, 31 Jan 2012 03:45:42 GMT |
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| in which structure are amino acids more spread out, helix or beta sheet? |
beta pleated sheet |
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aschefkind Tue, 31 Jan 2012 03:45:42 GMT |
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| alpha helixes are usually left handed or right handed? |
right handed b/c it minimizes steric clashes |
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aschefkind Tue, 31 Jan 2012 03:38:41 GMT |
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| Ramachandran |
he made a torsion angle diagram which showed that the only preferable arrangement makes alpha helix or beta pleated sheet |
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aschefkind Tue, 31 Jan 2012 03:38:41 GMT |
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| almost all proteins have ______ type of peptide bonds |
TRANS b/c cis can have steric clashes between R groups |
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aschefkind Tue, 31 Jan 2012 03:38:41 GMT |
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| 3 characteristics of peptide bonds |
-planar -double bond character (strong, short) -uncharged (not impeded by charge repulsion) |
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aschefkind Tue, 31 Jan 2012 03:38:41 GMT |
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| how do plants, animals, and fungi differ from each other? |
in how they get food. plants- photosynthesis animals- ingestion and internal digestion fungi- external digestion by secreting digestive enzymes and then absorbtion |
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aschefkind Tue, 31 Jan 2012 02:28:33 GMT |
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| How can you detect the presence of phage in a soil sample? |
test the ability of the phage to lyse bacterial host cells. place the sample in a culture of E. Coli bacteria. If phages are present, they will create clear zones in the lawn of bacteria |
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aschefkind Tue, 31 Jan 2012 02:28:33 GMT |
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| lactose intolerance is due to...? |
lack of the enzyme lactase, which can break down the beta-1,4 linkage in lactose |
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aschefkind Mon, 30 Jan 2012 06:40:33 GMT |
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| saturated fatty acids are solid or liquid at room temperature? |
solid! |
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aschefkind Mon, 30 Jan 2012 06:40:31 GMT |
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| unsaturated fatty acids are solid or liquid at room tempature? |
liquid! |
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aschefkind Mon, 30 Jan 2012 06:40:31 GMT |
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| main function of steroids? |
cell signaling! |
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aschefkind Mon, 30 Jan 2012 06:40:31 GMT |
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| main use of phospholipids? |
biological membranes! |
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aschefkind Mon, 30 Jan 2012 06:40:31 GMT |
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| function of triglycerides? |
energy storage! |
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aschefkind Mon, 30 Jan 2012 06:40:31 GMT |
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| glycerols are primary components in which two types of lipids? |
triglycerides and phospholipids |
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aschefkind Mon, 30 Jan 2012 06:40:30 GMT |
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| glyceraldehydes can be reduced to... |
glycerol! (which is a primary alcohol) |
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aschefkind Mon, 30 Jan 2012 06:40:30 GMT |
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glyceraldehyde has how many carbons...? what's bonded to the top carbon? |
3 carbons! top one is double bonded to an O and single bonded to a H |
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aschefkind Mon, 30 Jan 2012 06:40:30 GMT |
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| pKa= |
log(1/K) |
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aschefkind Mon, 30 Jan 2012 06:40:30 GMT |
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| lactose intolerance is due to...? |
lack of the enzyme lactase, which can break down the beta-1,4 linkage in lactose |
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aschefkind Mon, 30 Jan 2012 06:40:17 GMT |
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| saturated fatty acids are solid or liquid at room temperature? |
solid! |
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aschefkind Mon, 30 Jan 2012 06:39:34 GMT |
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| unsaturated fatty acids are solid or liquid at room tempature? |
liquid! |
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aschefkind Mon, 30 Jan 2012 06:39:07 GMT |
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| main function of steroids? |
cell signaling, regulation, protection! |
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aschefkind Tue, 31 Jan 2012 05:20:55 GMT |
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| main use of phospholipids? |
biological membranes! |
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aschefkind Mon, 30 Jan 2012 06:39:07 GMT |
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| function of triglycerides? |
energy storage! |
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aschefkind Mon, 30 Jan 2012 06:39:07 GMT |
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| glycerols are primary components in which two types of lipids? |
triglycerides and phospholipids |
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aschefkind Mon, 30 Jan 2012 06:37:18 GMT |
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| glyceraldehydes can be reduced to... |
glycerol! (which is a primary alcohol) |
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aschefkind Mon, 30 Jan 2012 06:37:18 GMT |
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glyceraldehyde has how many carbons...? what's bonded to the top carbon? |
3 carbons! top one is double bonded to an O and single bonded to a H |
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aschefkind Mon, 30 Jan 2012 06:37:18 GMT |
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| pKa= |
log(1/K) |
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aschefkind Mon, 30 Jan 2012 06:37:18 GMT |
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| components of a phospholipid: |
(2 fatty acids+a glycerol)+phosphate+alcohol hydrophobic hydrophillic |
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aschefkind Sat, 28 Jan 2012 20:19:19 GMT |
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| Future biodiesel fuel may come from.... |
triglycerides from plants or algae, or extracting fatty acids and converting them to esters with methanol |
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aschefkind Sat, 28 Jan 2012 20:19:19 GMT |
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| Omega-3/Omega-6 |
when there are lots of double bonds in a fatty acid (polyunsaturated), they are counted from the end (the right side). if first double bond is on the 3rd Carbon, it's an Omega-3; if the first one is on the 6th carbon, it's an Omega-6. These fats are actually very healthy and are found in fish. They assist in brain function, growth and development, and reduce the risk of heart disease |
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aschefkind Sat, 28 Jan 2012 20:16:42 GMT |
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| structural diff between saturated and unsaturated fats |
saturated have only carbon-carbon single bonds and are therefore straight unsaturated have one or more carbon-carbon double bonds and are therefore bent |
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aschefkind Sat, 28 Jan 2012 20:16:42 GMT |
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| ester linkage is between... |
glycerol and fatty acid |
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aschefkind Sat, 28 Jan 2012 20:10:35 GMT |
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| components of triglycerides |
one glycerol+3 fatty acids chain lengths usually between 14-24 carbons |
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aschefkind Sat, 28 Jan 2012 20:10:35 GMT |
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| 3 major types of lipids |
steroids triglycerides phospholipids |
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aschefkind Sat, 28 Jan 2012 20:10:35 GMT |
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| Roles of lipids: |
-major component of biological membranes -energy source and storage -signaling molecules -structural/architectural |
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aschefkind Sat, 28 Jan 2012 20:10:34 GMT |
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| Lipids (operational definition) |
water-insoluble biomolecules that are highly soluble in organic solvents, such as chloroform |
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aschefkind Sat, 28 Jan 2012 20:06:48 GMT |
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| ethanol biofuel is obtained through.... |
fermentation of sugars |
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aschefkind Sat, 28 Jan 2012 20:06:48 GMT |
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| Why can't mammals digest wood? |
they lack the enzyme which can degrade the beta-1,4 linkage in cellulose |
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aschefkind Sat, 28 Jan 2012 20:06:48 GMT |
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| type of linkage in cellulose |
beta-1,4 |
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aschefkind Sat, 28 Jan 2012 20:06:48 GMT |
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| Cellulose |
polysaccharide structural element in plant cell walls completely unbranched! |
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aschefkind Mon, 30 Jan 2012 07:53:33 GMT |
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| type of linkage that causes straight chain in glycogen and starch |
alpha-1,4 |
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aschefkind Sat, 28 Jan 2012 20:03:49 GMT |
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| type of linkage that causes branches in glycogen and starch |
alpha-1,6 |
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aschefkind Sat, 28 Jan 2012 20:03:49 GMT |
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| Starch |
storage form of glucose in PLANTS branched, but less so compared to glycogen |
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aschefkind Sat, 28 Jan 2012 20:03:49 GMT |
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| glycogen |
storage form of glucose in ANIMALS highly branched! |
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aschefkind Sat, 28 Jan 2012 19:57:20 GMT |
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| lactose is a disaccharide made up of.... |
glucose+galactose (with a beta linkage) |
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aschefkind Sat, 28 Jan 2012 19:57:20 GMT |
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| bacteria break down lactose using the enzyme ________ |
Beta-galactosidase |
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aschefkind Sat, 28 Jan 2012 19:57:20 GMT |
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| bond between monosaccharides is called.... |
glycosidic linkage |
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aschefkind Sat, 28 Jan 2012 19:57:20 GMT |
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| alpha vs. beta monosaccharides |
determined by orientation of aldehyde group |
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aschefkind Sat, 28 Jan 2012 19:49:02 GMT |
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| Linear vs. Ring forms of monosaccharide |
Ring forms are more stable and predominant under physiological conditions (linear forms are <1%) Ring formed by reaction between Hydroxyl group and aldehyde group at carbon 5 |
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aschefkind Sat, 28 Jan 2012 19:36:32 GMT |
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| Hydroxide group on the left of the second to last carbon is a ____ isomer |
L isomer |
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aschefkind Sat, 28 Jan 2012 19:36:32 GMT |
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| Hydroxide group on the right of the second to last carbon is a ____ isomer |
D isomer (most sugars are in this form) |
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aschefkind Sat, 28 Jan 2012 19:36:32 GMT |
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| Chirality |
asymmetrical, therefore it matters whether something is on the left or right this is the case for carbons in carbohydrates |
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aschefkind Sat, 28 Jan 2012 23:51:21 GMT |
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| what is a sugar? |
a polyhydroxyl aldehyde or a ketone with 3 or more carbons |
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aschefkind Sat, 28 Jan 2012 19:23:01 GMT |
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| Typical numbers of carbons in a monosaccharide |
3-9 |
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aschefkind Sat, 28 Jan 2012 19:23:01 GMT |
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| How many monosaccharides in oligosaccharides? |
3-20 |
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aschefkind Sat, 28 Jan 2012 19:20:55 GMT |
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| Uses of carbohydrates |
-Energy source, energy stores, metabolic intermediates -Structural framework of RNA and DNA -Structural elements in the cell walls of bacteria and plants -Linked to proteins and lipids |
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aschefkind Sat, 28 Jan 2012 19:20:55 GMT |
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| both function and shape of macromolecules are determined by... |
sequence and chemical properties of monomers |
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aschefkind Sat, 28 Jan 2012 19:20:55 GMT |
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| Hydrolysis reaction |
Water is consumed and a dimer breaks apart into two monomers. |
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aschefkind Sat, 28 Jan 2012 19:20:55 GMT |
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| Condensation reaction |
water is a byproduct and two molecules become connected |
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aschefkind Sat, 28 Jan 2012 19:17:12 GMT |
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| Nucleic acid monomer... |
nucleotide |
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aschefkind Sat, 28 Jan 2012 19:16:41 GMT |
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| Carb monomer... |
monosaccharide |
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aschefkind Sat, 28 Jan 2012 19:16:41 GMT |
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| Protein monomer... |
amino acid |
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aschefkind Sat, 28 Jan 2012 19:16:41 GMT |
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| 4 types of macromolecules... |
proteins, lipids, carbs, nucleic acids |
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aschefkind Sat, 28 Jan 2012 19:15:03 GMT |
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| aldehydes get oxidized to... |
CARBOXYLLIC ACID
C-C-C=O II O-H |
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aschefkind Tue, 31 Jan 2012 05:16:31 GMT |
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| secondary alcohols get oxidized to... |
KETONES O II C-C-C |
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aschefkind Sat, 28 Jan 2012 19:13:33 GMT |
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| primary alcohols get oxidized to... |
ALDEHYDES
C-C-C=O I H |
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aschefkind Sat, 28 Jan 2012 19:13:33 GMT |
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| Carbon chain with hydroxyl group in the middle... |
SECONDARY alcohol |
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aschefkind Sat, 28 Jan 2012 19:13:33 GMT |
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| Carbon chain with hydroxyl group on the end... |
PRIMARY alcohol |
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aschefkind Sat, 28 Jan 2012 19:13:33 GMT |
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| Sulfhydryl |
-SH class of compounds: thiols |
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aschefkind Sat, 28 Jan 2012 19:09:34 GMT |
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| Phosphato |
O O P O O class of compounds: organic phosphates |
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aschefkind Sat, 28 Jan 2012 19:09:34 GMT |
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| Amino |
H-N-H class of compounds: amines |
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aschefkind Sat, 28 Jan 2012 19:09:34 GMT |
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| Carboxyl |
OH-C=O class of compounds: carboxyllic acids |
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aschefkind Sat, 28 Jan 2012 19:09:34 GMT |
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| Keto |
C=O class of compounds: Ketones |
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aschefkind Sat, 28 Jan 2012 17:52:09 GMT |
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| Aldehydes |
H-C=0 class of compounds: aldehydes |
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aschefkind Sat, 28 Jan 2012 17:52:09 GMT |
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| Hydroxyl |
-OH class of compounds: alchohols |
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aschefkind Sat, 28 Jan 2012 17:52:09 GMT |
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| salt bridge |
COO- group connected to an NH3 group in proteins |
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aschefkind Sat, 28 Jan 2012 17:52:09 GMT |
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| tails of phospholipid bilayer are... |
hydrophobic |
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aschefkind Sat, 28 Jan 2012 17:30:19 GMT |
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| heads of phospholipid bilayer are... |
hydrophillic |
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aschefkind Sat, 28 Jan 2012 17:30:19 GMT |
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| 4 types of non-covalent interactions (by decreasing strength) |
ionic, H bond, hydrophobic, van der waals |
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aschefkind Mon, 30 Jan 2012 08:00:29 GMT |
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| Kinesin |
motor protein which drives movement down microtubule tracks (walks them) |
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aschefkind Sat, 28 Jan 2012 17:22:15 GMT |
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| 6 elements most commonly found in biology... |
C,H,N,O,P,S |
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aschefkind Sat, 28 Jan 2012 17:22:15 GMT |
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| Microtubules |
-hollow cylinders made of TUBULIN (alpha and beta) -causes chromosome movement during mitosis and meiosis -also causes vesicle movement |
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aschefkind Sat, 28 Jan 2012 17:22:15 GMT |
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| Intermediate Filaments |
-proteins with coiled-coil domains -nuclear lamins are one example |
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aschefkind Sat, 28 Jan 2012 17:19:24 GMT |
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| Microfilaments |
-made of ACTIN, have a positive end (which grows) and negative end (which does not grow) -drives shape changes and cell movement -also involved in muscle contractions |
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aschefkind Sat, 28 Jan 2012 17:19:24 GMT |
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| 3 components of cytoskeleton (by increasing size): |
Microfilaments, Intermediate Filaments, Microtubules |
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aschefkind Sat, 28 Jan 2012 17:19:24 GMT |
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| final product of photosynthesis is... |
starch |
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aschefkind Sat, 28 Jan 2012 17:19:24 GMT |
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| role of thylakoid |
transport of electrons during photosynthesis |
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aschefkind Sat, 28 Jan 2012 17:13:31 GMT |
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| Glyoxosomes |
found ONLY in plants -performs lipid metabolism (quickly converts fats into useable materials) |
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aschefkind Sat, 28 Jan 2012 17:13:31 GMT |
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| Peroxisome |
-all eukaryotes -single membrane -NOT derived from the secretory pathway -detox of peroxides (like H2O2) |
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aschefkind Sat, 28 Jan 2012 17:15:23 GMT |
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| Vacuole |
-single membrane -in plants, there is a very large central vacuole which serves as a hydrolytic compartment and as an expandable "space" |
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aschefkind Sat, 28 Jan 2012 17:13:31 GMT |
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| Chloroplast |
-site of photosynthesis -double membrane -inner fluid called stroma -pancake-like thylakoids make up stacks called grana |
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aschefkind Sat, 28 Jan 2012 17:09:18 GMT |
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| Reasons for endosymbiont theory of mitochondria/chloroplasts |
-size -DNA/RNA -double membrane - in japan, a single cell eukaryote was discovered which had ingested an algae and taken up use of its chloroplast basically |
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aschefkind Sat, 28 Jan 2012 17:14:44 GMT |
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| Mitochondria |
-double membrane -site of cellular respiration/ energy production -contains ribosomes/DNA |
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aschefkind Sat, 28 Jan 2012 17:09:18 GMT |
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| Where are enzymes in lysosomes synthesized? |
first they are made in the RER, then they get sent to the golgi, finally to the lysosome |
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aschefkind Sat, 28 Jan 2012 17:09:18 GMT |
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| lysosome |
filled with hydrolytic enzymes to lysis foreign particles like viruses |
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aschefkind Sat, 28 Jan 2012 17:03:00 GMT |
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| Why can't prokaryotic cells perform post-translational modification? |
because they have no golgi/ER which perform this function in eukaryotic cells |
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aschefkind Sat, 28 Jan 2012 17:03:00 GMT |
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| exocytosis |
export of matter out of the cell proteins on the surface of vesicles help to direct them to the correct location |
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aschefkind Sat, 28 Jan 2012 17:03:00 GMT |
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| endocytosis |
import of matter into the cell phagocytosis=particulate matter pinocytosis="cellular drinking" receptor mediated endocytosis (budding off of plasma membrane) |
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aschefkind Sat, 28 Jan 2012 17:03:00 GMT |
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| region of golgi closest to plasma membrane |
trans |
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aschefkind Sat, 28 Jan 2012 16:52:14 GMT |
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| region of golgi closest to nucleus |
cis |
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aschefkind Sat, 28 Jan 2012 16:52:14 GMT |
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| function of golgi body... |
processing and sorting of proteins destined for other cell compartments |
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aschefkind Sat, 28 Jan 2012 16:52:14 GMT |
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| Flattened sacs of golgi body are called.... |
cisternae |
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aschefkind Sat, 28 Jan 2012 16:52:14 GMT |
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| Smooth ER |
proteins are further processed, site of synthesis of lipids and steroids no ribosomes on surface |
0 |
aschefkind Sat, 28 Jan 2012 16:42:06 GMT |
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| Rough ER |
has ribosomes studded on its surface. proteins come here for processing (often the addition of sugar groups) |
0 |
aschefkind Sat, 28 Jan 2012 16:42:06 GMT |
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| Nuclear Pore Complex |
selectively permeable barrier through the nuclear envelope. if something has the correct nuclear localization sequence (NLS), it can undergo regulated transport via accessory proteins and get in also, if something is small enough. |
0 |
aschefkind Sat, 28 Jan 2012 16:42:06 GMT |
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| Nuclear Lamina |
Protein meshwork inside the nucleus which functions like the cytoskeleton |
0 |
aschefkind Sat, 28 Jan 2012 16:42:06 GMT |
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| What is the difference between euchromatin and heterochromatin? |
Euchromatin: gene rich, decondensed outside of mitosis
Heterochromatin: gene poor, very condensed, often located in nuclear periphery, is used to separate DNA |
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aschefkind Fri, 27 Jan 2012 06:56:10 GMT |
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| What are the two types of chromatin? |
Euchromatin and Heterochromatin |
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aschefkind Fri, 27 Jan 2012 06:56:10 GMT |
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| What is the nuclear plasm filled with? |
chromatin |
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aschefkind Fri, 27 Jan 2012 06:56:10 GMT |
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| What is the nuclear plasm? |
part of the nucleus that is outside the nucleolus |
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aschefkind Fri, 27 Jan 2012 06:56:10 GMT |
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| function of ribosomes? |
protein synthesis |
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aschefkind Fri, 27 Jan 2012 06:54:21 GMT |
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| Places where ribosomes are found? |
Rough ER, in cytosol, in other organelles, e.g. chloroplast, mitochondria |
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aschefkind Fri, 27 Jan 2012 06:54:21 GMT |
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| Nucleolus |
located inside nucleus site of ribosomal biogenesis and assembly |
0 |
aschefkind Fri, 27 Jan 2012 06:54:21 GMT |
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| Nuclear Membrane |
2 phosphilipid bilayers, many pores |
0 |
aschefkind Fri, 27 Jan 2012 06:54:21 GMT |
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| What differentiates membranes from one another? |
the proteins embedded on them |
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aschefkind Fri, 27 Jan 2012 06:51:54 GMT |
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| What is it called when a substance has conflicting chemical properties? |
Amphipathic |
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aschefkind Fri, 27 Jan 2012 06:51:54 GMT |
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| What is the phospholipid bilayer composed of? |
Hydrophopic Tails, Hydropphillic Heads |
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aschefkind Fri, 27 Jan 2012 06:51:54 GMT |
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| What is the plasma membrane made of? |
Phospholipid Bilayer |
0 |
aschefkind Fri, 27 Jan 2012 06:51:54 GMT |
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| Eukaryotic Cells |
contains various membrane-bound organelles such as nucleus, vacuole, golgi body subgroups are plant, animal, fungi plasma membrane, sometimes with cell wall |
0 |
aschefkind Fri, 27 Jan 2012 06:49:35 GMT |
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| Gram Positive |
Very thick cell wall No outer membrane |
0 |
aschefkind Fri, 27 Jan 2012 06:49:35 GMT |
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| Gram Negative |
layer of cell wall made of peptidoglycan, layer of porous outer membrane |
0 |
aschefkind Fri, 27 Jan 2012 06:49:35 GMT |
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| Prokaryotic Cells |
No defined nucleus, subgroups are bacteria and archaea, no membrane-bound organelles, can be gram negative or gram positive |
0 |
aschefkind Fri, 27 Jan 2012 06:49:35 GMT |
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| Eukaryotic Cells |
contains various membrane-bound organelles such as nucleus, vacuole, golgi body subgroups are plant, animal, fungi plasma membrane, sometimes with cell wall |
0 |
aschefkind Fri, 27 Jan 2012 06:48:38 GMT |
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| Gram Positive |
Very thick cell wall No outer membrane |
0 |
aschefkind Fri, 27 Jan 2012 06:48:38 GMT |
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| Gram Negative |
layer of cell wall made of peptidoglycan, layer of porous outer membrane |
0 |
aschefkind Fri, 27 Jan 2012 06:48:38 GMT |
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| Prokaryotic Cells |
No defined nucleus, subgroups are bacteria and archaea, no membrane-bound organelles, can be gram negative or gram positive |
0 |
aschefkind Fri, 27 Jan 2012 06:48:38 GMT |
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