Cell Communication Test Flash Cards

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Explain the s-t path involving cAMP.	ligand>G-prot recept>g-prot>adenyl cyclase>cAMP>protein kinase A>other relay mol.	0	zeetrit Mon, 12 Dec 2011 03:01:33 GMT
Explain the s-t path involving Ca+ ions as 2nd messengers.	Ligand>g-protein receptor or t-k receptor>phospholipase C>PiP2(which breaks into)<DAG and IP3(IP3 triggers)>Ca channal in ER memb>Ca2+ ions through channel>calmodulin>other relay mol>cell response	0	zeetrit Mon, 12 Dec 2011 03:01:33 GMT
List the four most common types of receptors and how they work.	G-protein-linked receptors: Ligand binds to this receptor, causing it to change shape, bind to a G-protein and facilitate the replacement of GDP with GTP on the G-protein, thereby activating it to transduct the signal further down the s-t pathway. Tyrosine-Kinase Receptors: A ligand binds to one of each of two receptors. This causes the two T-K receptors to aggregate and form a dimer. The tyrosine kinase domain on each of the receptors then phosphorylates the tyrosine molecules on the other receptor. These tyrosine molecules can then activate relay molecules which continue to relay the message. Ion-Channel Receptors: A ligand binds to this receptor and causes it to form a transmembrane channel. This allows ions to move in or out of the cell and trigger an s-t path. Cytoplasmic Receptors: These receptors are found in the cytoplasm instead of the cell membrane and recieve signals via small, hydrophobic ligands that pass through the cell membrane. A good example of a ligand that binds to this kind of receptor is a hormone.	0	zeetrit Mon, 12 Dec 2011 03:01:33 GMT
List+describe the three types of cell signaling	Autocrine: Cell emits a signal that causes a response in the same cell (self signaling). Paracrine: Cell emits a signal that causes a response in cells near it (local signaling). Includes synaptic signaling. Long-distance/Hormonal Signaling: Cell emits a signal (usually in the form of a hormone) that enters the bloodstream and is distributed throughout the body. Note: Cells may also communicate via cytosol passing between cell junctions/plasmodesmata.	0	zeetrit Mon, 12 Dec 2011 03:01:33 GMT
List in order + describe the three steps of cell communication and the five main molecules involved.	reception-->transduction-->response ligand>receptor>relay molecules and second messengers>molecule causing cellular response	0	zeetrit Mon, 12 Dec 2011 03:01:33 GMT

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name: Cell Communication Test
num users: 1
num cards: 5
created on: December 11, 2011
last updated: December 11, 2011

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