| front |
back |
revisions |
lasted changed by |
history |
| Deep brain stimulation (DBS)? |
ELECTRODES IN BRAIN USED TO BLOCK SYMPTOM CAUSING NERVE SIGNALS; TOTAL SUPPRESSION OF TREMOR IN 1/3-1/2 OF PATIENTS |
0 |
MichaelMorano Tue, 22 Feb 2011 00:37:59 GMT |
 |
| Stereotaxic surgery? |
TO ABOLISH AREAS OF BASAL GANGLIA TO REDUCE TREMOR AND RIGIDITY |
0 |
MichaelMorano Tue, 22 Feb 2011 00:37:59 GMT |
|
*Used in early PD with L-dopa
*Most effective on tremors and rigidity? |
ANTICHOLINERGICS |
0 |
MichaelMorano Tue, 22 Feb 2011 00:35:19 GMT |
|
| Dopamine agonist medications? |
*ACT ON POST SYNAPTIC DOPAMINE RECEPTORS
*REDUCE RIGIDITY AND BRADYKINESIA |
0 |
MichaelMorano Tue, 22 Feb 2011 00:35:19 GMT |
|
| Side effects of Levodopa (L-dopa)? |
GI, CONFUSION, HYPOTENSION, DYSURIA, SLEEP DISTURBANCES |
0 |
MichaelMorano Tue, 22 Feb 2011 00:35:19 GMT |
|
| Symptoms of PD? |
*CIRCULATORY: VENOUS POOLING, LE EDEMA; ORTHOSTATIC HYPOTENSION IS COMMON (CAN BE WORSENED WITH L-DOPA
*NUTRITION: MALNOURISHMENT DUE TO SWALLOWING PROBLEMS, CONTRIBUTES TO FATIGUE
*DECUBITUS ULCERS
*SKIN: DERMATITIS FROM EXCESSIVE SWEATING AND OILY SKIN |
0 |
MichaelMorano Tue, 22 Feb 2011 00:35:19 GMT |
|
| The inital effects of L-dopa is sometimes referred to as what? |
HONEYMOON PERIOD |
0 |
MichaelMorano Tue, 22 Feb 2011 00:26:13 GMT |
|
True/False
It often takes L-dopa a long time to initially show it's positive effects? |
FALSE
THE INITIAL FUNCTIONAL IMPROVEMENT IS OFTEN DRAMATIC |
0 |
MichaelMorano Tue, 22 Feb 2011 00:26:13 GMT |
|
| What is the primary benefit of L-dopa? |
ALLEVIATING BRADYKINESIA AND RIGIDITY (WITH LESS EFFECT ON TREMORS) |
0 |
MichaelMorano Tue, 22 Feb 2011 00:26:13 GMT |
|
| Why is it necessary to give a pt high doses of L-dopa? |
BECAUSE 99% OF IT IS METABOLIZED BEFORE IT REACHES THE BRAIN |
0 |
MichaelMorano Tue, 22 Feb 2011 00:26:13 GMT |
|
| A metabolic precursor of dopamine that is able to cross the blood-brain barrier and raise the level of striatal dopamine in the basal ganglia? |
L-DOPS (LEVODOPA) |
0 |
MichaelMorano Tue, 22 Feb 2011 00:22:44 GMT |
|
| Bradyphrenia? |
*A DISORDER OF INTELLECTUAL FUNCITON
*CHARACTERIZED BY A SLOWING OF THOUGHT AND INFORMATION PROCESSING |
0 |
MichaelMorano Tue, 22 Feb 2011 00:22:44 GMT |
|
| Why are there visual disturbances with PD? |
BECAUSE OF COVENTIONAL DRUGS (IE: ANTICHOLINERGIC DRUGS) |
0 |
MichaelMorano Tue, 22 Feb 2011 00:22:44 GMT |
|
| What are the effects on the autonomic NS due to PD? |
*EXCESSIVE PERSPIRATION
*DROOLING
*THERMOREGULATORY DIFFICULTY
*DECREASED GI TRACT MOTILITY
*ORTHOSTATIC HYPOTENSION
*LOW BP |
0 |
MichaelMorano Tue, 22 Feb 2011 00:22:44 GMT |
|
| Masklike face? |
HYPOMIMIA |
0 |
MichaelMorano Tue, 22 Feb 2011 00:11:50 GMT |
|
| Gait disturbance? |
*FESTINATING GAIT (SHORT STRIDE LENGTH WITH INCREASE IN SPEED); LACK OF EXTENSION OF LE; LACK OF TRUNK ROTATION; DIFFICULTY STARTING AND STOPPING |
0 |
MichaelMorano Tue, 22 Feb 2011 00:11:50 GMT |
|
| Micrographia? |
SMALL HANDWRITING; DIFFICULT TO READ |
0 |
MichaelMorano Tue, 22 Feb 2011 00:11:50 GMT |
|
| Poor motor planning? |
APRAXIA |
0 |
MichaelMorano Tue, 22 Feb 2011 00:11:50 GMT |
|
| Signs of resting tremors? |
*INITIAL CLINICAL SIGN IN 70% OF PD
*RESTING TREMOR; PILL ROLLING TREMOR
*CAN BE SEEN IN FACE, FEET, LIPS, AND TONGUE
*LESS SEVERE WHEN PATIENT IS RELAXED, DIMINISHED BY VOLUNTARY EFFORT; DISAPPEARS DURING SLEEP
*WORSENED BY STRESS, FATIGUE, EXCITEMENT
*OFTEN FLUCTUATES IN INTENSITY AND FREQUENCY |
0 |
MichaelMorano Tue, 22 Feb 2011 00:06:38 GMT |
|
| Signs of bradykinesia? |
*SLOWNESS OF MOVEMENT
*DIFFICULTY INITIATING MOTION; DECREASES IN SPEED, RANGE, AND AMPLITUDE OF VOLUNTARY AND AUTOMATIC MOVEMENT
*INCREASED RACTION TIME AND MOVEMENT TIME
*IMPAIRED COORDINATION, ESPECIALLY FINE MOTOR SKILLS
*SEVERE BRADYKINESIA=AKINESIA (FREEZING) |
0 |
MichaelMorano Tue, 22 Feb 2011 00:06:38 GMT |
|
| Sings and symptoms of rigidity in a PD pt? |
*PATIENT C/O "HEAVINESS OR STIFFNESS"
*OCCURS IN AGONIST AND ANTAGONIST; CONSTANT REGARDLESS OF TAST, AMPLITUDE, SPEED OF MOTION
*MAY BE UNEQUAL IN DISTRIBUTION
*MAY BE EXTREMITY OR TRUNCAL; PROXIMAL AFFECTED FIRST
*INCREASED WITH FATIGUE, EMOTIONAL STRESS, OR MENTAL CONCENTRATION
*LEAD PIPE AND COGWHEEL |
0 |
MichaelMorano Tue, 22 Feb 2011 00:06:38 GMT |
|
| What are the cardinal signs of PD? |
*BRR
*BRADYKINESIA
*RIGIDITY
*RESTING TREMOR |
0 |
MichaelMorano Tue, 22 Feb 2011 00:06:38 GMT |
|
| A decrease in dopamine and an increase in acetylcholine will result in what? |
RESULTS IN EXCESSIVE EXCITATORY OUTPUT AND GENERALIZED ACTIVATION OF SKELETAL MUSCLE |
0 |
MichaelMorano Mon, 21 Feb 2011 22:24:33 GMT |
|
True/False
Acetylcholine is inhibitory? |
FALSE
EXCITITORY |
0 |
MichaelMorano Mon, 21 Feb 2011 22:24:33 GMT |
|
True/False
Dopamine is inhibitory? |
TRUE |
0 |
MichaelMorano Mon, 21 Feb 2011 21:21:40 GMT |
|
| What chemical is destroyed in the body due to PD? |
DOPAMINE (NEUROTRANSMITTER) |
0 |
MichaelMorano Mon, 21 Feb 2011 21:21:40 GMT |
|
| Metabilic causes of PD? |
DISORDERS OF CALCIUM METABOLISM MAY CAUSE CALCIFICATION OF THE BASAL GANGLIA (IE: HYPOTHYROIDISM, HYPOPARATHYROIDISM) |
0 |
MichaelMorano Mon, 21 Feb 2011 21:21:40 GMT |
|
| Late onset of idiopathic PD is what? |
SPORADIC |
0 |
MichaelMorano Mon, 21 Feb 2011 21:21:40 GMT |
|
| Early onset of idiopathic PD is what? |
FAMILIAL |
0 |
MichaelMorano Mon, 21 Feb 2011 21:11:38 GMT |
|
| Idiopathic PD? |
*MOST COMMON FORM OF PD
*SLOWLY PROGRESSIVE WITH LONG SUBCLINICAL PERIOD; AVERAGE LIFE EXPECTANCY POST ONSET OF SYMPTOMS 13-14 YEARS.
*EARLY ONSET OFTEN FAMILIAL
*LATE ONSET OFTEN USUALLY SPORADIC |
0 |
MichaelMorano Mon, 21 Feb 2011 21:11:38 GMT |
|
| Caused by other NS diseases (supranuclear palsy, alzheimer's, creutzfield jacob dx)? |
ATYPICAL PD |
0 |
MichaelMorano Mon, 21 Feb 2011 21:11:38 GMT |
|
| Caused by exposure to certain chemicals or industrial poisons? |
TOXIC PARKINSON'S DISEASE |
0 |
MichaelMorano Mon, 21 Feb 2011 21:11:38 GMT |
|
