Drug Ch 8 Flash Cards

 
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Indefinite commitment to a hospital has been declared _____________. unconstitutional 0 rlgray Wed, 20 Oct 2010 13:48:44 GMT view revision history
For some psychiatrists the perscription ______ has replaced the _______ as a primary tool. pad

coach
0 rlgray Wed, 20 Oct 2010 13:48:44 GMT view revision history
The biggest limitation to the usefulness of lithium is that patients simply do not: like to take them 0 rlgray Wed, 20 Oct 2010 13:46:31 GMT view revision history
3 factors slowed the acceptance of lithium in the US: salt substitute poisoning

mania was not seen a major problem

economic and how drugs are intro into US
0 rlgray Wed, 20 Oct 2010 13:46:31 GMT view revision history
In 1949, _________ published the beneficial use of lithium. John Cade 0 rlgray Wed, 20 Oct 2010 13:46:31 GMT view revision history
When there is a possibility of suicide, ______ is thus the obvious choice, and it is possible to use both drug and ______ treatment simultaneously. ECT

ECT
0 rlgray Wed, 20 Oct 2010 13:46:31 GMT view revision history
The fact that drugs with a wide variety of initial biochemical effects are all about _________ effective. equally 0 rlgray Wed, 20 Oct 2010 13:40:53 GMT view revision history
There are major _________ effects associated with the use of antidepressants when their use is stopped. withdrawal 0 rlgray Wed, 20 Oct 2010 13:40:53 GMT view revision history
Only ______ (/) of the 74 studies submitted to the FDA since 1987 in support of the new drug applications for 12 antidepressants found positive results in favor of the tested drug. half 0 rlgray Wed, 20 Oct 2010 13:40:53 GMT view revision history
Antidepressant sales _______ in 2004 and s005 due to concerns about increased risk of _________ among children. declined

suicide
0 rlgray Wed, 20 Oct 2010 13:40:53 GMT view revision history
In 2006, 7 different antidepressants were among the 100 most prescribed drugs in the US, led by ______, _____, and _______. Lexapro

Zoloft

Effexor
1 rlgray Wed, 20 Oct 2010 14:22:00 GMT view revision history
The __________ antidepressants were found in a search for better phenothiazine antipsychotics. tricyclic 0 rlgray Wed, 20 Oct 2010 13:35:41 GMT view revision history
Because aged cheeses are one source of tyramin, this is often referred to as the _________ reaction. cheese 0 rlgray Wed, 20 Oct 2010 13:35:41 GMT view revision history
Iproniazid was removed from sale in ________ (yr)after being implicated in at least _____ fatalities. 1961

54
1 rlgray Wed, 20 Oct 2010 14:26:37 GMT view revision history
Iproniazod is a" MAO 1 rlgray Wed, 20 Oct 2010 13:29:53 GMT view revision history
MAO(acronym) are ___________. monoamine oxidas inhibitor

antidepressants
0 rlgray Wed, 20 Oct 2010 13:29:40 GMT view revision history
The biggest single reason for patients stopping the use of antipsychotics was ___________ decision. patient 0 rlgray Wed, 20 Oct 2010 13:29:40 GMT view revision history
The drug trials that demonstrate the benefits of antipsychotics typically last _____ or ______ weeks. 6 or 8 1 rlgray Wed, 20 Oct 2010 14:18:23 GMT view revision history
late-appearing abnormal movements: tardive dyskinesia 0 rlgray Wed, 20 Oct 2010 13:25:30 GMT view revision history
_____________ is the most serious complication of antipsychotic drug treatment. Tardive dyskinesia 0 rlgray Wed, 20 Oct 2010 13:25:30 GMT view revision history
The most common side effect of antipsychotic medication involves the __________ dopamine pathway. nigrostriatal 0 rlgray Wed, 20 Oct 2010 13:25:30 GMT view revision history
Low white blood cell count of unknown origin: agranulocytosis 0 rlgray Wed, 20 Oct 2010 13:25:30 GMT view revision history
2 positive aspects of the antipsychotics are: no drug dependency

extremely difficult to us them and commit suicide
0 rlgray Wed, 20 Oct 2010 13:22:55 GMT view revision history
negative symptoms of schizophrenia: lack of emotion
social isolation
lack of initiative
0 rlgray Wed, 20 Oct 2010 13:22:55 GMT view revision history
positive symptoms of schizophrenia: hallucinations
delusions
diorganized speech
behavior
0 rlgray Wed, 20 Oct 2010 13:22:55 GMT view revision history
Clozapine differed from other anipsychotic drugs in two ways: less pseudoparkinsonism

it worked when other drugs didn't
0 rlgray Wed, 20 Oct 2010 13:22:55 GMT view revision history
It is now well accepted that the initial effect of antipsychotic drugs is to block D2 _________ receptors. dopamine 0 rlgray Wed, 20 Oct 2010 13:17:12 GMT view revision history
Another aspect of evaluating the effectiveness of drug treatment in antipsychotics is determining the incidence of _________ when treatment is discontinued. relapse 0 rlgray Wed, 20 Oct 2010 13:17:12 GMT view revision history
In a NIMH study, after 6 weeks ___% of acute schizophrenics receiving phenothiazines showed either moderate or marked improvement. 75 0 rlgray Wed, 20 Oct 2010 13:17:12 GMT view revision history
A term meaning 'taking hold of the nervous system': neuroleptic 0 rlgray Wed, 20 Oct 2010 13:17:12 GMT view revision history
In the US the antipsychotics were generally called ____________. tranquilizers 0 rlgray Wed, 20 Oct 2010 13:10:21 GMT view revision history
Credit is usually given to a French surgeon,___________, who first tested antipsychotics in conjunction with surgical anesthesia. Henri Laborit 0 rlgray Wed, 20 Oct 2010 13:10:20 GMT view revision history
Sedation of severely disturbed patients by drugs that make them drowsy and slow them down has been referred to as the use of a _______________. chemical straitjacket 0 rlgray Wed, 20 Oct 2010 13:10:20 GMT view revision history
ECT electroconvulsive therapy 0 rlgray Wed, 20 Oct 2010 13:10:20 GMT view revision history
______ is still used with severely depressed patients who do not respond to medication. ECT 0 rlgray Wed, 20 Oct 2010 13:04:19 GMT view revision history
In 1933, __________ of vienna induced comas in some schizophhrenics by administering insulin. Manfred Sakel 0 rlgray Wed, 20 Oct 2010 13:04:19 GMT view revision history
_________ serum was discovered through narcosis therapy. Truth 0 rlgray Wed, 20 Oct 2010 13:04:19 GMT view revision history
The later discovery of ____________ that could cure syphilis virtually eliminated this particular type of treatment. antibiotics 0 rlgray Wed, 20 Oct 2010 13:04:19 GMT view revision history
Before 1950 most of the psychotic patients were suffering from general _______, a syphilitic infection of the nervious system. paresis 0 rlgray Wed, 20 Oct 2010 12:55:58 GMT view revision history
_______disorder refers to the appearance of depressed or manic symptoms. Mood 0 rlgray Wed, 20 Oct 2010 12:55:58 GMT view revision history
Schizophrenia should probably be translated as _________ mind. shattered 0 rlgray Wed, 20 Oct 2010 12:55:58 GMT view revision history
____________ disorders are simply those for which there is no known or obvious physical cause. Functional 0 rlgray Wed, 20 Oct 2010 12:55:58 GMT view revision history
An organic disorder is one that has a known ________ cause. physical 0 rlgray Wed, 20 Oct 2010 12:52:27 GMT view revision history
In recent yrs, psychiatrists have increasingly used selective ________ inhibitors, classified as _____________ to tread ocd and other anxiety disorders. reuptake

antidepressants
0 rlgray Wed, 20 Oct 2010 12:52:27 GMT view revision history
The fact that _________ drugs can be effective in controlling symptoms, if not curing them has lent strength to supporters of the ___________ model. psychoactive

medical
0 rlgray Wed, 20 Oct 2010 12:52:27 GMT view revision history
__________ model: the patient appears with a set of symptoms and on the basis of these symptoms a _________ is made as to which disease the patient is suffering from. Medical

diagnosis
0 rlgray Wed, 20 Oct 2010 12:52:27 GMT view revision history

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